- صفحه اصلی
- products
- Drug Raw Material
- Excipients drug
- Tablet Fillers
- Calcium Phosphate Tribasic
Calcium Phosphate Tribasic
Functional Category
Anticaking agent; buffering agent; dietary supplement; glidant; tablet and capsule diluent.
Applications in Pharmaceutical Formulation or Technology
Tribasic calcium phosphate is widely used as a capsule diluent and tablet filler/binder in either direct-compression or wet-granulation processes. The primary bonding mechanism in compaction is plastic deformation. As with dibasic calcium phosphate, a lubricant and a disintegrant should usually be incorporated in capsule or tablet formulations that include tribasic calcium phosphate. In some cases tribasic calcium phosphate has been used as a disintegrant. It is most widely used in vitamin and mineral preparations as a filler and as a binder. It is a source of both calcium and phosphorus, the two main osteogenic minerals for bone health. The bioavailability of the calcium is well known to be improved by the presence of cholecalciferol. Recent research reports that combinations of tribasic calcium phosphate and vitamin D3 are a cost-effective advance in bone fracture prevention. In food applications, tribasic calcium phosphate powder is widely used as an anticaking agent. See Section 18. See also Calcium phosphate, dibasic dihydrate.
Description
The PhEur 6.4 states that tribasic calcium phosphate consists of a mixture of calcium phosphates. It contains not less than 35.0% and not more than the equivalent of 40.0% of calcium. The USP32– NF27 specifies that tribasic calcium phosphate consists of variable mixtures of calcium phosphates having the approximate composition 10CaO3P2O5H2O. This corresponds to a molecular formula of Ca5(OH)(PO4)3 or Ca10(OH)2(PO4)6.
Tribasic calcium phosphate is a white, odorless and tasteless powder.
برچسب ها : tribasic calcium phosphate ,
medicinal tribasic calcium phosphate ,
sale of tribasic calcium phosphate ,
purchase of tribasic calcium phosphate ,
seller of tribasic calcium phosphate ,
price of tribasic calcium phosphate ,
preparation of tribasic calcium phosphate ,
use of tribasic calcium phosphate ,
producer of tribasic calcium phosphate ,
what is tribasic calcium phosphate ,
tribasic calcium phosphate